Female obesity linked to lower rates of live birth and embryo implantation in the uterus

An analysis of almost 10,000 first cycles of egg donation treatment at one of Europe's largest IVF centres shows that female obesity reduces the receptivity of the uterus to embryo implantation and thereby compromises reproductive outcome. The investigators report that excess female weight "impairs human reproduction" and that "the reduction of uterine receptivity is one of the mechanisms involved". As a result they advise weight reduction before pregnancy in any type of conception, including ovum donation.

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